Similar to the majority of herbs, forskolin is created from a variety of active compounds; however, it is the single tuberous roots of the forskolin that is the most active component. This tuberous root of forskolin is a highly beneficial component that has been used greatly in experimental research studies.
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Studies have shown that the roots of the forskolin herb have the ability to increase levels of CAMP in animals. CAMP is a contraction for the cellular messenger compound cyclic adenosine monophosphate. Research also shows that many healthcare providers utilize forskolin in patient treatment, including eye drops and IVs. The compound can also be used in powder form to treat a variety of complex health conditions. The most popular use of forskolin is in fat reducing formulas; however, it can also be used in products that reduce blood pressure, overcome indigestion difficulties, and maintenance of testosterone levels.
Forskolin can also be used as a supplementary treatment, as determined by a thorough and popular research study. The research was conducted at the University of Kansas, and findings indicated that the compound is effective for losing weight. Males were studied and the methodology included intake of 250 mg of forskolin-containing coleus twice per day. A placebo group was also used to validate results. The results showed that overweight and obese males in the control group lost an average of 7.8 times more body fat than males in the placebo group. Results also showed that the males in the control group gained 35% more bone mass and increased available testosterone in the body by 34%. The control subjects showed an overall improvement in physical mental health and body composition.
The effectiveness of forskolin can be attributed to its ability to stimulate the enzyme adenylyl cyclase directly. This rapid stimulation can activate additional enzymes in cells and tissues; as well as positively affect the concentration of the CAMP compound.
Forskolin is a unique compound in that the changes in CAMP levels are reversible, unlike many other herbal treatment. The reversible effect is possible through the use of additional cellular receptors, such as beta adrenoreceptors. Forskolin is a uncomplicated and dependable compoung which is often used for control groups in clinical studies that are studying the role of CAMP in any capacity.